Aquaporin-3 (AQP3) is a membrane transporter of water and glycerol expressed in plasma membranes in the basal layer keratinocytes of epidermis in normal skin.
水通道蛋白 3 (AQP3) 是一種水和甘油的膜轉運蛋白,在正常皮膚表皮基底層角質形成細胞的質膜中表達。
AQP3-knockout mice have reduced stratum corneum water content and elasticity compared with wild-type mice, as well as impaired wound healing and epidermal biosynthesis.
與野生型小鼠相比,AQP3 敲除小鼠的角質層含水量和彈性降低,傷口癒合和表皮生物合成受損。
PSS is characterized by painless, continual, spontaneous skin peeling (exfoliation) due to a separation of the outermost layer of the epidermis (stratum corneum) from the underlying layers.
特徵是無痛、持續、自發的皮膚剝落(剝落),由於表皮的最外層(角質層)與下面的層分離。
Overview. Dry skin (xerosis cutis) can cause the skin on your face to peel
概述。皮膚乾燥(皮膚乾燥症)會導致您臉上的皮膚脫皮
The reductions of serine protease activity are a consistent theme in dry skin
絲氨酸蛋白酶活性的降低是乾性皮膚的一致主題
~~~
serine protease activity, was significantly enhanced by IL-4
IL-4 顯著增強絲氨酸蛋白酶活性
Furthermore, dry skin results when lipids are depleted and there is not enough water in the stratum corneum for it to function properly.
此外,當脂質耗盡並且角質層中沒有足夠的水使其正常運作時,會導致皮膚乾燥。
小結1:
水通道蛋白 3 (AQP3) 是一種水和甘油的膜轉運蛋白
在正常皮膚表皮基底層角質形成細胞的質膜中表達
AQP3 敲除小鼠的角質層含水量降低
所以脂質耗盡並且角質層中沒有足夠的水
可能和AQP3表達有問題有關
Angiotensin converting enzyme 2 (ACE2), the entry receptor for SARS-CoV-2, is expressed in epidermal keratinocytes.
血管緊張素轉換酶 2 (ACE2) 是 SARS-CoV-2 的進入受體,在表皮角質形成細胞中表達。
小結3:
所以皮膚脫皮可能和AQP3受病毒攻擊有關